Xyosted Card

Paying for XYOSTED?

CO-Pay Card Program

XYOSTED Co-pay Assistance Program provides financial support to most commercially insured patients to assist with out-of-pocket costs of XYOSTED. Eligible patients* may pay as little as $25 co-pay for each prescription filled. This card is valid for up to 13 fills per calendar year.

* Eligibility restrictions: Offer not valid for prescriptions reimbursed under any federal or state healthcare program, including Medicare, Medicaid, or any state medical assistance programs. Offer void where prohibited by law, taxed, or restricted. Offer only valid in the USA. Maximum benefit up to $125 for each prescription filled. Halozyme reserves the right to rescind, revoke, or amend this offer at any time without notice. By using this co-pay card, you demonstrate that you understand and agree to comply with the terms and conditions of this offer as put forth on this co-pay assistance card.

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XYOSTED4You

Cash Program XYOSTED4YOU

XYOSTED4YOU is a Cash Program, designed to allow eligible patients† who have been prescribed  XYOSTED by their doctor, to access XYOSTED even if they do not have health insurance or their healthcare plan does not cover XYOSTED.

 

†Eligibility restrictions: Must be 18 years or over with a valid prescription for XYOSTED® (testosterone enanthate). Must be a U.S. resident with a valid U.S. shipping address. Additional shipping charges may apply. Offer not valid for prescriptions reimbursed under any private insurance or any federal or state healthcare program, including, but not limited to, Medicare, Medicaid, Tricare, or any state medical assistance programs. Purchases made under this program cannot be claimed in any Part D True Out of Pocket Cost (TrOOP) Submission. Patients are responsible for reporting use of this program to any private insurer, health plan or third-party payer. The XYOSTED4YOU Cash Program is not health insurance. Cannot be combined with other offers or programs. Offer void where prohibited by law, taxed, or restricted. Halozyme reserves the right to rescind, revoke, or amend this offer at any time without notice. By enrolling in this program, you demonstrate that you understand and agree to comply with the terms and conditions set forth herein and any additional Terms and Conditions set by specialty pharmacy regarding purchases made under this program.

 

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RXCrossroads By McKesson

Mail In Rebate Program

If your pharmacist is unable to provide the co-pay or coinsurance savings at the time you fill your prescription, you can still take advantage of this program if eligible.

CLICK TO GET YOUR REBATE

 

used Auto-injector
Disposal Program

 

Halozyme, is offering a free disposal program for your auto-injectors. 
A complete disposal kit will be sent by mail after the completion of a quick form.

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FAQs & Resources

Still have unanswered questions about TRT and XYOSTED? Explore our FAQs section.

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INDICATION/WHAT IS XYOSTED?

XYOSTED is a prescription medicine that contains testosterone. XYOSTED is used to treat adult men who have low or no testosterone due to certain medical conditions.

It is not known if XYOSTED is safe and effective for use in children younger than 18 years old. Improper use of XYOSTED may affect bone growth in children.

It is not known if XYOSTED is safe or effective to treat men who have low testosterone due to aging.

XYOSTED is a controlled substance (CIII) because it contains testosterone that can be a target for people who abuse prescription medicines. Keep your XYOSTED in a safe place to protect it. Never give your XYOSTED to anyone else. Selling or giving away this medicine may harm others and it is against the law.

XYOSTED is not meant for use by women.

IMPORTANT SAFETY INFORMATION

Do not use XYOSTED if you:

  • Are a man who has breast cancer.
  • Have or might have prostate cancer.
  • Are a woman who is pregnant. XYOSTED may harm your unborn baby.
  • Are allergic to XYOSTED or to any ingredients in XYOSTED including testosterone or sesame oil.

What should I tell my healthcare provider before using XYOSTED?

Before you use XYOSTED, tell your healthcare provider about all of your medical conditions, including, if you have any of the following: high blood pressure or are being treated for high blood pressure, or have heart problems, high red blood cell count, urinary problems due to an enlarged prostate, kidney or liver problems, a history of mental health illness including suicidal thoughts or actions, depression, anxiety or mood disorder, or problems breathing while you sleep (sleep apnea).

Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Using XYOSTED with other medicines can affect each other. Especially, tell your healthcare provider if you take insulin, medicines that decrease blood clotting (blood thinners), corticosteroids or medicines for pain and cold. Know the medicines you take. Ask your pharmacist for a list of all your medicines if you are not sure. Show your list to your healthcare provider and pharmacist when you get a new medicine.

How should I use XYOSTED?

  • See the detailed Instructions for Use for Information about how to use XYOSTED.
  • Use XYOSTED exactly as your healthcare provider tells you to take it.
  • Your healthcare provider will show you or your caregiver how to inject XYOSTED. You should not inject XYOSTED until you have been trained on the proper way to use it.

What are the possible side effects of XYOSTED?

XYOSTED can cause serious side effects including:

  • Increase in red blood cell count, hematocrit or hemoglobin. High red blood cell counts increase the risk of clots, strokes, and heart attacks. You may need to stop XYOSTED if your red blood cell count increases. Your healthcare provider should check your red blood cell count, hematocrit and hemoglobin while you use XYOSTED.
  • If you already have an enlarged prostate, your signs and symptoms may get worse while using XYOSTED. This can include: increased nighttime urination, trouble starting urination, more frequent urination, feeling an urge to urinate, having a urine accident, and being unable to pass urine or weak urine flow
  • Increased risk of prostate cancer. Your healthcare provider should check you for prostate cancer or any other prostate problems before you start and while you use XYOSTED.
  • Blood clots in the legs or lungs. Signs and symptoms of a blood clot in your leg can include leg pain, swelling or redness. Signs and symptoms of a blood clot in your lungs can include difficulty breathing or chest pain.
  • Increase in blood pressure. XYOSTED can increase your blood pressure. Increases in blood pressure can increase the risk of heart attack or stroke over time. If your blood pressure increases while on XYOSTED, blood pressure medicines may need to be started. If you are taking blood pressure medicines, new blood pressure medicines may need to be added or your current blood pressure medicines may need to be adjusted to control your blood pressure. If your blood pressure cannot be controlled, XYOSTED may need to be stopped. Your healthcare provider will monitor your blood pressure while you are being treated with XYOSTED.
  • Abuse. Testosterone can be abused, when taken at higher than prescribed doses and when used with other anabolic androgenic steroids. Abuse can cause serious heart and psychological side effects.
  • In large doses XYOSTED may lower your sperm count.
  • Liver problems. Symptoms of liver problems may include nausea or vomiting, yellowing of your skin or whites of your eyes, dark urine or pain on the right side of your stomach area (abdominal pain).
  • Swelling of your ankles, feet, or body, with or without heart failure. This may cause serious problems for people who have heart, kidney or liver disease.
  • Enlarged or painful breasts.
  • Problems breathing while you sleep (sleep apnea).
  • Change in mood. Talk to your healthcare provider if you have changes in mood or behavior including, new or worsening depression, or suicidal thoughts.

Call your healthcare provider right away if you have any of the serious side effects listed above.

The most common side effects of XYOSTED include: red blood cell increase, prostatic specific antigen (PSA) increase (a blood test for prostate cancer), increased blood pressure, and injection site reactions including bruising, bleeding, redness and headache.

Other side effects include more erections than are normal for you or erections that last a long time. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of XYOSTED. For more information, ask your healthcare provider or pharmacist.

For more information, go to www.XYOSTED.com
or call 1-844-XYOSTED (1-844-996-7833).
To report side effects to the FDA,
visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see the full Prescribing Information and Medication Guide.
April 2025 Update.